Biomedical Engineering

In the context of an aging society and the challenges posed by the COVID-19 pandemic, ensuring a healthy life expectancy has become a pressing social concern. Amidst the pandemic's impact on medical systems worldwide, the need for advancements in early diagnosis, minimally invasive treatments, and infectious disease countermeasures has been reaffirmed. The demand for practical solutions, including new drugs, medical devices, and healthcare systems, is vocalized by healthcare professionals. To address these challenges, engineering researchers play a crucial role in swiftly translating their technological innovations into medical applications. In this book, cutting-edge researchers introduce biomedical engineering from materials, devices, imaging, and information. The chapter contributors are major members of the Research Center for Biomedical Engineering, Japan. This text discusses topics on biomaterials (Chapters 1 to 3), medical devices (Chapters 4 to 11), basic medicine and dentistry (Chapters 12 to 15), and medical systems (Chapters 16 and 17). All of the topics are important areas in biomedical engineering.

Akihiro Miyauchi is a professor at the Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Japan. He received his PhD from Tokyo Institute of Technology, Japan, in 1995. With a wealth of experience, he served at Hitachi Ltd from 1986 to 2017 and held the position of visiting scientist at the Massachusetts Institute of Technology from 1995 to 1996. Prof. Miyauchi's research focuses on semiconductor process, nanoimprint, and biomimetics. Hiroyuki Kagechika is a professor and director at the Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University. He received his PhD in pharmaceutical sciences from the University of Tokyo, Japan, in 1989. Prof. Kagechika's major research interest is in the development of functional organic molecules in the fields of medicinal chemistry, chemical biology, and materials sciences. He has developed various novel bioactive compounds, including a drug for acute promyelocytic leukemia.

1. Manipulation of mechanical and functional properties of the Ti-Au-based shape memory alloys by transition metal introductions 2. Ceramics for bone repair and cancer therapy 3. Hydrophilic treatment using atmospheric pressure low-temperature plasma 4. Microwave Imaging Algorithms for Breast Cancer Detection 5. Synergy of data glove based motion tracking and functional electrical stimulation for rehabilitation and assisted learning 6. Motion estimation from surface EMG signals using multi-array electrodes 7. Low power wireless transmitter with quadrature backscattering technique 8. Representation by extended reality in X-ray three-dimensional imaging 9. Refractive index measurement by photodiode with surface plasmon antenna and its application to biosensing 10. Application of THz spectroscopy for crystal-structure refinement of bio-related molecules and functional materials 11. Organic molecule-containing electrically conductive electron beam resist for organic biosensors with nanostructures 12. mRNA medicines and mRNA vaccines 13. Fabrication of decellularized tissue for biomedical application 14. Bioengineering challenges in regenerative medicine: biofunctional materials design 15. Development of Etak, an ethoxysilane-based immobilized antibacterial and antiviral agent 16. A real-time computer-aided diagnosis system with quantitative staging on customizable embedded digital signal processor 17. Medical image analysis