Review of Sleep Medicine

Designed as both a rigorous review textbook and a trusted clinical reference, Review of Sleep Medicine, 5th Edition, edited by Dr. Alon Avidan, provides a comprehensive and structured synthesis of the rapidly evolving field of sleep medicine. Whether the goal is board preparation, fellowship training, or enhancing day-to-day clinical decision-making, this authoritative resource equips clinicians and trainees with the knowledge framework needed to excel. Organized for efficient learning and high-yield review, the text is divided into two complementary sections: Part One delivers concise yet academically robust review chapters that distill the essential science and clinical principles underlying sleep medicine-from foundational neurobiology and circadian physiology to complex diagnostic and therapeutic strategies. Part Two features 24 carefully constructed practice examinations, each accompanied by detailed answer explanations that not only identify the correct response but also illuminate the clinical reasoning, evidence base, and diagnostic logic behind each question. Written and curated by internationally recognized leaders in sleep medicine, the Fifth Edition reflects a multidisciplinary and globally informed perspective, integrating insights from neurology, pulmonary medicine, psychiatry, psychology, internal medicine, pediatrics, and sleep technology.- Comprehensive coverage of the entire field of sleep medicine, including epidemiology, neurobiology of sleep and circadian rhythms, pathophysiology of sleep disorders, clinical evaluation, diagnostic testing, treatment strategies, and long-term outcomes- Fully updated and expanded content, including advances in pediatric sleep medicine; the intersection of sleep and psychiatric disorders; contemporary approaches to obstructive sleep apnea management; and sleep in systemic medical illness, including a new chapter on COVID-19 and sleep- New mini sleep atlas for sleep stage scoring, providing visual reinforcement through polysomnographic tracings, EEG illustrations, and practical scoring examples- Hundreds of board-style review questions in an online interactive learning tool, available in both study mode and simulated testing mode- Rich visual learning resources, including figures, diagnostic algorithms, polysomnography tracings, actigraphy examples, sleep diaries, tables, and high-yield key points that clarify complex concepts and facilitate rapid review- A valuable academic and clinical resource for a wide spectrum of professionals involved in sleep medicine, including sleep medicine fellows, neurologists, pulmonologists, psychiatrists, internists, clinical psychologists, nurse practitioners, physician assistants, and registered polysomnographic technologists- An enhanced eBook version is included with purchase, providing convenient digital access to the full text, figures, and references, with advanced search capabilities, note-taking and highlighting features, and read-aloud functionality-supporting flexible learning across clinical, academic, and study environments

Dr. Avidan is Professor of Neurology at UCLA where he serves as Director of the UCLA Sleep Disorders Center. He completed his Neurology Residency at the Georgetown University Medical Center, and Fellowship in Sleep Medicine at the Cleveland Clinic. He served as Visiting Professor of Neurology Education in the Department of Neurology at the Mayo Clinic College of Medicine in Rochester, MN, and was selected to receive the 2014 American Academy of Sleep Medicine (AASM) Excellence in Education Award, for career contributions to education in sleep medicine. Dr. Avidan has published over 100 manuscripts on sleep disorders and had co-authored several books with Dr. Meir Kryger (a giant in the field). He is a Diplomate of the American Board of Psychiatry and Neurology, the American Board of Sleep Medicine, and a Diplomate in the Specialty of Sleep Medicine by the American Board of Psychiatry and Neurology. He is a Fellow of the American Academy of Neurology and the American Academy of Sleep Medicine.

SECTION I: REVIEW 1. Introduction to Sleep Medicine 2. Sleep Phylogenic Evolution and Ontogeny 3. Highlights of Sleep Neuroscience 4. Normal Human Sleep-Wake Patterns 5. Normal Sleep Physiology (Respiratory and Cardiac Physiology) 6. Genetics in Sleep Medicine 7. Assessment and Evaluation Tools in Sleep Medicine 8. An Overview of Polysomnography 9. Sleep Stage Scoring 10. Sleep Deprivation 11. The Insomnias 12. Central Nervous System Hypersomnia 13. Sleep-Related Breathing Disorders: Clinical Features and Evaluation 14. Sleep-Related Breathing Disorders Treatment 15. Cardiac Monitoring and Scoring in Polysomnography 16. Circadian Rhythm Disorders 17. Diagnosis and Treatment of Parasomnias 18. Sleep Related Movement Disorders 19. Overview of Electroencephalography and Epilepsy 20. Sleep and Neurological Disorders 21. Sleep and Psychiatric Disorders 22. Sleep and Medical Disorders 23. Sleep and COVID19 24. Overview of Pediatric Sleep Medicine 25. Pediatric Sleep Disordered Breathing 26. Pediatric Insomnia 27. Pediatric Parasomnias and Movement Disorders 28. Pediatric Central Disorders of Hypersomnia 29. Sleep and Sleep Disorders in Older Adults 30. Sleep in Women 31. Sleep in Diverse Communities 32. Pharmacotherapy of Sleep Promoting Agents 33. Medication Effects on Sleep 34. Overview of Sleep Practice Parameters SECTION II. ASSESSMENT 35. Practice Test: Normal Sleep 36. Practice Test: Mechanisms of Sleep Neuroscience: A Symphony of Many Parts 37. Practice Test: Sleep-Wake Timing Disorders: Key Questions. 38. Practice Test: Tools in Clinical Sleep Medicine 39. Practice Test: Polysomnography Pearls 40. Practice Test: Sleep Stage Scoring 41. Practice Test: Artifacts 42. Practice Test: Insomnia Clinical Pearls 43. Practice Test: Hypersomnia Case Studies 44. Practice Test: Pulmonary Sleep Clinical Case Studies 45. Practice Test: Cardiology in Sleep Medicine 46. Practice Test: Clinical Cases: Circadian Rhythm Sleep-Wake Disorders 47. Practice Test: REM and Non-REM Parasomnias 48. Practice Test: Sleep-Related Movement Disorders 49. Practice Test: Seizures and Sleep 50. Practice Test: Neurology in Sleep Medicine, Polysomnography Case-Based Assessment 51. Practice Test: Psychiatry Clinical Case Studies 52. Practice Test: Sleep and Medical Disorders, and Special Populations 53. Practice Test: Pediatric Sleep Medicine 54. Practice Test: Pharmacology Mechanisms 55. Practice Test: Statistics and Epidemiology in Sleep Medicine 56. Practice Test: Knowing your Sleep Practice Parameters 57. Practice Test: Quality Measures in Sleep Medicine 58. Practice Test: Medicolegal Issues in Sleep Medicine List of Abbreviations Appendix A. Cardiac Arrhythmias B. Basic statistical principles C. Interpreting Medical Data