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Selected for Doody's Core Titles® 2024 in PsychiatryAnatomy of Neuropsychiatry: The New Anatomy of the Basal Forebrain and Its Implications for Neuropsychiatric Illness, Second Edition, builds upon reprised classic chapters by Lennart Heimer and Gary Van Hoesen describing the cortical and subcortical structure and functional involvements of several functional-anatomical macrosystems in the human forebrain, the existence of which obviates the vaunted heuristic value of the "limbic system" concept in the study of motivation and emotion. New narrative brings in important historical, philosophical, and histotechnical contexts, integration with novel technologies (e.g., optogenetics) and structures (e.g., rostromedial tegmental nucleus), a deeper dive into the interactions of forebrain and prospective cerebellar macrosystems with the reticular core of the brain, and current viewpoints on the essential role of macrosystems in motion, motivation, emotion, cognition, and neuropsychiatric well-being. - Presents discredited concept of the limbic system - Reviews the neuroanatomy of the basal forebrain, greater limbic lobe, and reticular core - Includes Clinical and Basic Science Boxes highlighting specific concepts, structures, and neuronal circuits from functional and clinical perspectives - Features 10 videos of dissections of human brain done by the late Lennart Heimer
Daniel S. Zahm works at Saint Louis University, St. Louis, MO, USA.
1. The limbic systemdan eroding concept in perpetual search for a definition and some key experimental neuroanatomical discoveries that have undermined it2. The anatomy of the basal forebrain3. The greater limbic lobe4. Focus on basal forebrain macrosystems5. Interfaces of macrosystems with the brainstem reticular formation, thalamus, and each other6. Macrosystems in motion, representation, value, emotion, and neuropsychiatric illness7. Cerebellum as a macrosystem8. Basal forebrain macrosystems as a fundamental organizing principle of vertebrate brain
