Glycopeptide Antibiotics

This work describes all known assays used to discover new glycopeptide antibiotics. It discusses practical techniques for screening, isolating and analyzing glycopeptide antibiotics, correlating structure-activity relationships with the mode of action. Every relevant chemical aspect of the carbohydrate components of glycopeptide antibodies is examined.

Ramakris Nagarajan

Glycopeptides - Classification, Occurrence and Discovery; Separation Methodology; Approaches to the Synthesis of the Vancomycin Aglycones; Chemistry of Carbohydrate Components; Structure-Activity Relationships of Vancomycin Antibiotics; Vancomycin and Related Glycopeptides - Resistance and Mode of Action; Analytical Quantitation and Characterization; Teicoplanin; Vancomycin - A Clinical Overview.