Quantifying Morphology and Physiology of the Human Body Using MRI

In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Each chapter offers comprehensive information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment. These novel techniques provide unique information about the electromagnetic and mechanical properties of tissues and introd

L. Tugan Muftuler

BRAIN: Quantifying Brain Morphology Using Structural Imaging. Quantifying Brain Morphology Using Diffusion Imaging. CMRO2 Mapping by Calibrated fMRI. Quantifying Functional Connectivity in the Brain. Brain MR Spectroscopy In Vivo: Basics and Quantitation of Metabolites. BODY: Quantitative Magnetic Resonance Imaging of Articular Cartilage and Its Clinical Applications. Quantitative Structural and Functional MRI of Skeletal Muscle. Quantitative Techniques in Cardiovascular MRI. Quantitative MRI of Tumors. Quantitative Measurements of Tracer Transport Parameters Using Dynamic Contrast-Enhanced MRI as Vascular Perfusion and Permeability Indices in Cancer Imaging. Evaluation of Body MR Spectroscopy In Vivo. Imaging Tissue Elasticity Using Magnetic Resonance Elastography. Imaging Conductivity and Permittivity of Tissues Using Electric Properties Tomography. Quantitative Susceptibility Mapping to Image Tissue Magnetic Properties. Index.