Thin Layer Chromatography in Chiral Separations and Analysis

Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo

University of Silesia, Katowice, Poland Lafayette College, Easton, Pennsylvania, USA

Introduction. Chirality. Commercial Stationary Phases for Enantioseparations. Planar Chromatographic Enantioseparations on Non-commercial CSPs. Planar Chromatographic Enantioseparations on Non-Commercial CCPs. Chiral Modifiers of Mobile Phases. An Overview of the Chiral Separation Mechanisms. Separation of Diastereoisomers by means of TLC. Selected Bottlenecks of Densitometric Detection with Chiral Analytes. Chirality of Pharmaceutical Product Racemates. Chiral Separation of the Selected ß-blockers. Chiral Separation of Aminoacid Enantiomers. Chiral Separation of NSAIDs. Determination of Components in Selected Drug Racemates. Chiral Separations using Marfey's Reagent.