Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process

This book provides a comprehensive review of synthesis and physicochemical and biological characterization of novel antibacterial biomaterials produced according to original procedures and aimed at medical applications such as wound dressing, soft and hard tissue implants, drug delivery devices, and carriers for cell cultivation. It is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professionals, science and engineering graduate students, academics, and industrial researchers. - Includes in-depth discussions on synthesis and physicochemical characterization of novel poly vinyl alcohol-based hydrogels aimed at wound dressings and soft tissue implants - Explores synthesis and physicochemical characterization of novel bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants - Reviews cytotoxicity and antibacterial activity of novel poly vinyl alcohol-based hydrogels aimed for wound dressing and soft tissue implants - Discusses cytotoxicity and antibacterial activity of bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants - Provides original fractional derivative models of drug release process from hydrogels and bioceramic coatings on metal surface and explores diffusion mechanism

Vesna Miškovi--Stankovi- is Professor at the Faculty of Ecology and Environmental Protection, University Union-Nikola Tesla, Belgrade, Serbia. She obtained her BSc, MSc, and PhD degrees in chemical engineering from the School of Technology and Metallurgy, University of Belgrade, Serbia, and postdoc fellowship from the University of Trento, Italy. She was Professor at the Faculty of Technology and Metallurgy, University of Belgrade. She was also Visiting Professor at the University of Trento, Italy; Ohio University, USA; Laval University, Canada; Shandong University, Jiangsu Normal University, and Fudan University, China; and Kyung Hee University, Seoul, South Korea. Her research activities include biomaterials, biomedicine, and electrochemistry. She is a member of the Academy of Engineering Sciences of Serbia and was listed among the top 2% of scientists in the world by Stanford University. Teodor Atanackovic is Professor Emeritus at the Department of Mechanics, Faculty of Technical Sciences, University of Novi Sad, Serbia, and a member of the Serbian Academy of Arts and Sciences. He works in theoretical mechanics and the application of fractional kinetics in pharmacology and dentistry. He was listed among the t-p 2% of scientists in the world by Stanford University.

1. Introduction. 2. Hydrogels Aimed for Wound Dressings and Soft Tissue Implants. 3. Hydroxyapatite-Based Coatings Aimed for Hard Tissue Implants. 4. Modeling of Drug Release Processes: Fractional Derivative Models and Comparison with Standard Models.